|
KMID : 0604520080340020083
|
|
Journal of the Society of Cosmetic Scientists of Korea
2008 Volume.34 No. 2 p.83 ~ p.92
|
|
|
A Study on Application for Cosmeceutical of Fagopyrum esculentum Extracts
|
|
Kim Jin-Young
Park Soo-Nam
|
|
|
Abstract
|
|
|
|
In this study, the antioxidative effects, inhibitory effects on tyrosinase and elastase and components of Fagopyrum esculetum extracts were investigated. Fagopyrum esculetum used for this study is hulls and dehulled seeds. The free radical(1,1-diphenyl-2-picrylhydrazyl radical, DPPH) scavenging activities() and reactive oxygen species(ROS) scavenging activities() of extract/fractions from Fagopyrum esculetum were measured. The aglycone() and ethyl acetate fractions() of hulls showed the most effective scavenging activities. The protective effects on the rose-bengal sensitized photohemolysis of human erythrocytes were investigated. The ethyl acetate fraction exhibited the most prominent cellular protective effect( at 10 ). The inhibitory effect of aglycone fraction of hull and dehulled seeds on tyrosinase were examined (, respectively). And The inhibitory effect of aglycone fraction of hull and dehulled seeds on elastase were investigated( respectively). But 50% ethanol extract rarely exhibited the inhibitory activity on tyrosinase and elastase. (+)-Catechin and (-)-epicatechin were contained in ethyl acetate fraction of dehulled seeds. And ethyl acetate fraction of hull contains flavonoids of hyperin, quercetin, rutin and so on. These results indicate that extract/fractions of Fagopyrum esculentum can function as antioxidants in biological systems, particularly skin exposed to UV radiation by scavenging and other ROS, and protect cellular membranes against ROS. Fagopyrum esculentum extract could be used as a new cosmeceutical for whitening and anti-wrinkle products.
|
|
|
KEYWORD
|
|
|
Fagopyrum esculentum, flavonoids, antioxidant, photohemolysis, cosmetics
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|